Coronavirus

Living like a semi-hermit helps. A couple of deer hunting sessions, one grocery store visit a week, a couple of visits a month for takeout and to various medicos (my usual preventive medicine in the late January to March timeframe each year), and maybe a HD or Lowes visit to start some honey-dos and that is it for me. Masked and washing hands after every stop. Won't start kayaking until May and its a solo.
You probably had it already.
 
Nah. I had an hellacious case of bronchitis in September 2019 while river cruising the Rhine but that was way before. Plus I had an antibody test in the spring of 2020- negative. Trust me, I get anything involving the respiratory system and I will know it.
 
Nah. I had an hellacious case of bronchitis in September 2019 while river cruising the Rhine but that was way before. Plus I had an antibody test in the spring of 2020- negative. Trust me, I get anything involving the respiratory system and I will know it.
Ex Smoker..??
 
As the J&J and AstraZeneca vaccines seem to be approaching their introductions, let's review how they differ from the Pfizer & Moderna vaccines. All of the vaccines end up "fooling" a person's cells to make and release the COVID-19 "Spike Protein". Once this protein is released, the person's immune system recognizes this foreign body, activating a complete immune response, including the production of antibodies against the Spike Protein. The end result is that if a person gets infected by COVID-19, this "primed" immune response can immediately begin to attack the invading COVID-19 viruses.

So how do they do this, here are the steps.

Basic differences:
  • AstraZeneca (AZ) and Johnson & Johnson (J&J) have the Spike Protein synthesis instructions embedded in the attenuated adenovirus' native DNA
  • Pfizer (PF) and Moderna (MD) have the messenger RNA (mRNA) instruction for Spike Protein synthesis enclosed in lipid nanospheres, which bypasses multiple cellular steps as you'll see below
  • AZ, MD, and PF are two dose vaccinations, J&J is a single dose
  • The attenuated adenovirus AZ and J&J vaccines are far easier to scale up than the mRNA PF and MDD vaccines
  • The Lipid Nanosphere mRNA vaccines have stringent shipping and storage conditions, including dry ice shipment for PF

1. Cellular Entry Mode: Attenuated Adenovirus: AZ, J&J Lipid Nanospheres: PF, MD

2. Changes to Host Cell DNA: AZ, J&J N/A: PF, MD

3. mRNA synthesis: AZ, J&J N/A: PF, MD

4. Spike Protein Synthesis: AZ, J&J PF, MD

5. Spike Protein Release: AZ, J&J PF, MD


Time for a picture to jog your collective memory to remember how cells make proteins from mRNA. It occurs in your cellular ribosomes, those little black dots in the rough endoplasmic reticulum.

The mRNA can be considered an instruction tape which runs through the ribosome where transfer RNA (tRNA) which is bound to the appropriate amino acid, come together to assemble the polypeptide chain of the COVID-19 Spike Protein. The whole system can be considered to be a cellular nanobot assembly line. Once the protein is completed, it's then released from the cell, activating your immune system.



View attachment 30125

If you had the option, which one would you pick?
 
If you had the option, which one would you pick?
I’ve already had my first Moderna vaccine which was my 1st choice by a hair. They are all so similar and effective that you can’t make a bad choice, with the exception of choosing not to get vaccinated, unless you truly have medical issues directly related to the actual chemical constituents in these vaccines.
 
Ex Smoker..??
Never. Gotta remember I was subjected to random urinalysis from 1971 through 2011 when I retired so I never did any of the other stupid stuff either.
I nearly died from lobar pneumonia in 1973 in my senior year at Hofstra, and had viral pneumonia as a kid in the 60s as well.
 
Last edited:
Brazilian Mutation now in the US. Is each country going to have their own? I’m sure there are multiple mutations of this virus already in the states already that we don’t even know about. I have a bachelors in Biology. I remember learning about it, but I was probably hungover at the time.
 
Brazilian Mutation now in the US. Is each country going to have their own? I’m sure there are multiple mutations of this virus already in the states already that we don’t even know about. I have a bachelors in Biology. I remember learning about it, but I was probably hungover at the time.
Benjamin, Benjamin, Benjamin...
1611617842204.png


This from a man that went to his Friday afternoon computer class quiz every week making sure he deeply inhaled more than a few times prior to class.

Remember one time sitting there thinking, "If I was a computer how would I calculate this?" Somehow I aced the class, it's a miracle that I even remember I took the class...
 
Fashion Statement aside - is this really any more effective?

 
Benjamin, Benjamin, Benjamin...
View attachment 30280

This from a man that went to his Friday afternoon computer class quiz every week making sure he deeply inhaled more than a few times prior to class.

Remember one time sitting there thinking, "If I was a computer how would I calculate this?" Somehow I aced the class, it's a miracle that I even remember I took the class...
I remember heading to my genetics class in such bad shape. I threw up in a planter on the second floor of the science wing before I made it into the classroom.

PS i was pretty skinny back then
 
📱 Fish Smarter with the NYAngler App!
Launch Now

Members online

Fishing Reports

Latest articles

Back
Top